RAF Typhoon FGR4s have operated alongside French aircraft in a coordinated attack targeting an subterranean weapons facility in Syrian territory used by the Daesh militant organization, according to the UK Ministry of Defence.
The facility, located using intelligence, was believed to be containing munitions and bombs, the statement said, and was situated in hills just to the north of the historic site of Palmyra in central Syria.
"Our fighter planes employed laser-guided Paveway IV weapons to strike a series of access tunnels providing entry to the facility... preliminary assessments are that the objective was successfully hit," the MoD said.
There was no evidence of any civilian casualties in the attack conducted Saturday night and each participating jet made a safe return, the MoD added.
The Typhoon FGR4s were backed up by a Voyager tanker plane.
IS - also known as the so-called Islamic State - imposed jihadist rule over large swathes of Iraq and Syria before its territorial defeat in 2019.
"This action demonstrates our UK leadership, and commitment to work closely with our allies, to stamp out any re-emergence of IS and their violent and radical beliefs in the area," UK Defence Secretary the minister said.
British military aircraft have conducted overwatch operations over Syria to "forestall any efforts to regroup" of Islamic State subsequent to its defeat at the Baghuz confrontation in the year 2019, the ministry said.
"I extend gratitude to the personnel of our armed forces who took part in this strike for their expertise and their bravery," Healey commented. "Including them were numerous UK service members stationed over Christmas and New Year. This operation, to remove dangerous terrorists who endanger our security, shows how UK forces are always on standby, all year round, ensuring Britain's security domestically and strong abroad."
Last December, the US military executed what it called a "massive strike" targeting Islamic State objectives in the country, after an assault claimed the lives of two US troops and a civilian linguist in the Palmyra area.
The United Nations says IS still has between 5,000 and 7,000 fighters in both countries.